Maternal High Fat Diet Activates Hepatic Interleukin 4 in Rat Male Offspring Accompanied by Increased Eosinophil Infiltration

Maternal High Fat Diet Activates Hepatic Interleukin 4 in Rat Male Offspring Accompanied by Increased Eosinophil Infiltration

Interleukin-4 (IL4) is activated as an immune response throughout an infection or tissue damage. Epigenetic programming of maternal high-fat (HF) eating regimen has long-term results within the offspring. Within the current examine, we investigated the epigenetic regulation of IL4 in a maternal HF eating regimen mannequin within the liver of grownup offspring.

Timed-pregnant Sprague-Dawley rats had been fed both management or HF eating regimen all through gestation and lactation. Offspring had been positioned on a management eating regimen after weaning, producing C/C and HF/C teams. The liver was collected at 12 weeks of age and adopted by histological and molecular evaluation to research the maternal programming results of IL4 by HF eating regimen.

Maternal HF eating regimen considerably induced mRNA expression and protein degree of IL4 whereas promoted hypomethylation of Il4 evaluating to the management group. Methylation-selective PCR (MSP) confirmed maternal HF eating regimen elevated RNA polymerase II, acetylation of histone H4, and dimethylation of Histone Three lysine Four on the +6kb area of Il4.

Furthermore, rat eosinophil marker, Siglec-F was elevated and co-localized with IL4 within the liver. In conclusion, our examine indicated that IL4 was elevated in liver cells in response to maternal HF eating regimen. This coincides with DNA hypomethylation together with chromatin reworking on the +6 kb of the three’ downstream area, in addition to an induced immune cell infiltration, particularly eosinophil infiltration, within the liver of offspring.

<em>Interleukin</em>-1 Receptor-Related Kinase <em>4</em> Deficiency in a Greek Teenager

Human interleukin- (IL-) 1 receptor-associated kinase 4 (IRAK-4) deficiency is a just lately described major immunodeficiency. It’s a uncommon, autosomal recessive immunodeficiency that impairs toll/IL-1R immunity, aside from the toll-like receptor (TLR) 3- and TLR4-interferon alpha (IFNA)/beta (IFNB) pathways. Case Report. We report the primary affected person in Greece with IRAK-Four deficiency.

From the age of eight months, she introduced with recurrent infections of the higher and decrease respiratory tract and pores and skin abscesses. For this, she had been repeatedly hospitalized and handled empirically with intravenous antibiotics. No extreme viral, mycobacterial, or fungal infections had been famous. Her immunological laboratory analysis revealed low serum IgA and restored in subsequent measurements; regular IgG, IgM, and IgE; and regular serum IgG subclasses.

Peripheral blood immunophenotyping by stream cytometry and dihydrorhodamine (DHR) take a look at revealed regular counts. She was capable of make purposeful antibodies in opposition to vaccine antigens, together with tetanus and diphtheria. She was administered with empirical IgG substitution for five years till the age of 12 years, and he or she has by no means skilled invasive bacterial infections thus far. DNA evaluation revealed a heterozygous variant within the affected person: c.823delT (p.S275fs  13 at protein degree) within the IRAK4 gene.

 Maternal High Fat Diet Activates Hepatic <em>Interleukin</em> <em>4</em> in Rat Male Offspring Accompanied by Increased Eosinophil Infiltration

Neural stem cells induce M2 polarization of macrophages via the upregulation of <em>interleukin</em>-<em>4</em>

Macrophages are divided into two sorts: M1- and M2-type macrophages. Each varieties of macrophages serve vital roles through the strategy of irritation. M1-type macrophages launch varied pro-inflammatory cytokines, akin to IL-1, IFN-γ and different inflammatory mediators, akin to nitric oxide, glutamate and reactive oxygen species to generate irritation. In distinction, M2-type macrophages counteract the pro-inflammatory M1 situations and promote tissue restore by secreting anti-inflammatory cytokines, akin to IL-10.

In spinal twine damage (SCI), an imbalance in M1/M2 macrophages results in irreversible tissue destruction. Thus, it’s essential to extend the variety of M2-type macrophages and promote M2 polarization of macrophages in SCI. Accordingly, on this examine an in vitro co-culture system was established to research the impact of neural stem cells (NSCs) on macrophages.

The outcomes of the current examine demonstrated that NSCs induced M2 polarization and suppressed M1 polarization of macrophages in an interleukin (IL)-4-dependent method. Moreover, the nuclear issue (NF)-κB/p65 signaling pathway was concerned within the M1 polarization of macrophages and NSCs suppressed the activation of the NF-κB/p65 pathway in an IL-4-dependent method to induce M2 macrophage polarization. These findings present extra perception into SCI and assist to establish novel therapy methods.

The function of <em>Interleukin</em>-<em>4</em> in COVID-19 related male infertility – A speculation

COVID-19 is a present-day complicated pandemic an infection with unpredictable ranges of morbidity and mortality in varied world populations. COVID-19 is related to the completely different comorbidities with its change in organic perform akin to inflicting coronary heart dysfunction through deregulating ACE-2 receptor, gastrointestinal threat through inflicting vomiting, diarrhea, and belly ache, continual kidney illness through proteinuria and hematuria, diabetes mellitus, liver damage through rising ALT, AST and bilirubin degree, lung damage, CNS threat, ocular threat, and most cancers threat. On this, we’re targeted on the COVID-19 related with male infertility.

A few of the research present that the sufferers of COVID-19 are related to impaired spermatogenesis. Impaired spermatogenesis through COVID-19 decreases the extent of testosterone by disturbing cytokines akin to TNF-α, IL-4, IL-6, and IL-12 and additional, attenuates the sperm rely. COVID-19 is inflicting irritation through TNF-α and interferons. IL-Four performs an eminent function within the activation of the JAK-STAT pathway and results in the disturbing pro-inflammatory cytokine in addition to additional trigger’s male infertility.

Th2 prompts the IL-Four via IgG and IgE and mediates apoptosis with the triggering of STAT signaling. The activated STAT signaling augments Batf/Irf4, and the Bach2/Batf pathway. However, SARS-CoV-2 is activating the extent of Th2 cells. So, we hypothesized that the augmented Th2 cells would disturb the extent of IL-4, JAK-STAT signaling, Batf/Irf4, and Bach2/Batf pathway.

BMP-2 Bone Morphogenetic Protein-2 Human Recombinant Protein, Monomer

PROTP12643-2 Regular: 20ug
EUR 317
Description: Bone Morphogenetic Protein-2 Human Recombinant produced in E.Coli is a monomeric, non-glycosylated, Polypeptide chain containing 115 amino acids (283-396) and having a molecular mass of 13009 Dalton. ;The BMP-2 is purified by proprietary chromatographic techniques.

ErbB2 ErbB-2 Human Recombinant Protein

PROTP04626-2 Regular: 20ug
EUR 317
Description: ErbB-2 Human Recombinant is a 43.4 kDa protein containing 397 amino acid residues of the human Herstatin, and an extra Methionine at N-Terminal (underlined), produced in E.coli.

IL17B Human, Interleukin-17B Human Recombinant Protein, Sf9

PROTQ9UHF5-2 Regular: 5ug
EUR 317
Description: IL17B Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 169 amino acids (21-180a.a.) and having a molecular mass of 19.2kDa (Molecular size on SDS-PAGE will appear at approximately 18-28kDa). IL17B is expressed with a 6 amino acid His-tag at C-Terminus and purified by proprietary chromatographic techniques.

IL15 Human, Interleukin-15 Human Recombinant Protein, HEK

PROTP40933-2 Regular: 10ug
EUR 317
Description: Interleukin-15 Human Recombinant produced in HEK cells is a glycosylated monomer, having a molecular weight of 12.8kDa due to glycosylation.;The IL15 is purified by proprietary chromatographic techniques.

IL-7 Interleukin-7 Human Recombinant Protein

PROTP13232-2 Regular: 10ug
EUR 317
Description: Interleukin-7 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 152 amino acids and having a molecular mass of 17.4 kDa. ;The IL-7 is purified by proprietary chromatographic techniques.

IL-10 Interleukin-10 Human Recombinant Protein

PROTP22301-2 Regular: 10ug
EUR 317
Description: Interleukin-10 Human Recombinant produced in E.coli is a single non-glycosylated polypeptide chains containing 161 amino acids each and having a molecular mass of 18.6kDa.;The IL-10 is purified by proprietary chromatographic techniques.

Recombinant Murine IL-2 Protein

PROTP04351-2 20ug
EUR 317
Description: IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant murine IL-2 is a 17.2 kDa protein, containing 149 amino acid residues.

Mouse FGF-2 Recombinant Protein

R00121-2 5ug/vial
EUR 259
Description: FGF basic (FGF2) is a multipotential fibroblast growth factor that stimulates and supports proliferation, migration and differentiation. Mouse FGF basic (FGF-2) Recombinant Protein is purified FGF basic (FGF-2) produced in yeast.

Chicken IL-2 Recombinant Protein

R00387-2 5ug/vial
EUR 259
Description: Interleukin-2 (IL-2) is a cytokine produced by T-helper cells in response to antigenic or mitogenic stimulation. It is required for T-cell proliferation and other activities crucial to the regulation of the immune response. Chicken IL-2 Recombinant Protein is purified interleukin-2 produced in yeast.

Recombinant Human TGF-Beta 2 (insect derived) Protein

PROTP61812-2 10ug
EUR 317
Description: The three mammalian isoforms of TGF-β, TGF-β1, β2, β3, signal through the same receptor and elicit similar biological responses. They are multifunctional cytokines that regulate cell proliferation, growth, differentiation and motility as well as synthesis and deposition of the extracellular matrix. They are involved in various physiological processes including embryogenesis, tissue remodeling and wound healing. They are secreted predominantly as latent complexes which are stored at the cell surface and in the extracellular matrix. The release of biologically active TGF-β isoform from a latent complex involves proteolytic processing of the complex and /or induction of conformational changes by proteins such as thrombospondin-1. TGF-β2 has been shown to exert suppressive effects on IL-2 dependent T-cell growth, and may also have an autocrine function in enhancing tumor growth by suppressing immuno-surveillance of tumor development. Recombinant human TGF-β2 is a 25.0 kDa protein composed of two identical 112 amino acid polypeptide chains linked by a single disulfide bond.
* Manufactured using (BTI-Tn-5B1-4) cells under license from the Boyce Thompson Institute for Plant Research, Inc.

IL1A Human, Interleukin-1 alpha Human Recombinant Protein, HEK

PROTP01583-2 Regular: 10ug
EUR 317
Description: Interleukin-1 alpha Human Recombinant produced in HEK cells is a glycosylated monomer, having a molecular weight of 18kDa due to glycosylation.;The IL1A is purified by proprietary chromatographic techniques.

IL-4 Interleukin-4 Human Recombinant Protein, CHO

PROTP05112-2 Regular: 10ug
EUR 317
Description: Interleukin-4 Human Recombinant produced in CHO is a single, non-glycosylated polypeptide chain containing 129 amino acids and having a molecular mass of 14 kDa, the glycosilation of IL-4 migrates as 18 kDa on SDS-PAGE.;The IL-4 is purified by proprietary chromatographic techniques.

IL-6 Interleukin-6 Recombinant Protein Human, CHO

PROTP05231-2 Regular: 20ug
EUR 317
Description: Interleukin-6 Human Recombinant produced in CHO is a 21-23kDa single, glycosylated polypeptide chain containing 183 amino acids.

IL-3 Interleukin-3 Human Recombinant Protein, Sf9

PROTP08700-2 Regular: 10ug
EUR 317
Description: Interleukin-3 Human Recombinant produced in insect cells is a single, glycosylated polypeptide chain containing 133 amino acids and having a molecular mass of 15000 Dalton. ;The IL-3 CSF is fused to a C-terminal His-tag (6x His) and purified by proprietary chromatographic techniques.

IL-9 Interleukin-9 Human Recombinant Protein, Sf9

PROTP15248-2 Regular: 10ug
EUR 317
Description: IL-9 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain (19-144 a.a.) including an 18 aa signal peptide (1-18 aa) and fused to a 6 aa His Tag at C-terminus containing a total of 150 amino acids and having a molecular mass of 14.5kDa.;IL9 shows multiple bands between 18-28kDa on SDS-PAGE, reducing conditions and purified by proprietary chromatographic techniques.

PLGF2 Human, Placenta Growth Factor-2 Human Recombinant Protein, CHO

PROTP49763-2 Regular: 25ug
EUR 317
Description: PLGF2 Human Recombinant (19-170 a.a.) produced in CHO is a disulfide-linked homodimeric, glycosylated, polypeptide chain containing 152 amino acids and having a molecular mass of 33kDa.;The PLGF-2 Human Recombinant protein is purified by proprietary chromatographic techniques.

B2M Human, Beta 2 Microglobulin Human Recombinant Protein, His Tag

PROTP61769-2 Regular: 5ug
EUR 317
Description: B2M Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 120 amino acids (1-119 a.a.) and having a molecular mass of 14 kDa. The B2M is fused to a 21 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.

AHSG Alpha-2-HS-Glycoprotein Human Recombinant Protein HEK

PROTP02765-2 Regular: 10ug
EUR 317
Description: AHSG Human Recombinant produced by transfected human cells is a single polypeptide chain containing 357 amino acids (19-367). AHSG is fused to an 8 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.

FGF-2 Fibroblast Growth Factor-Basic Human Recombinant Protein

PROTP09038-2 Regular: 50ug
EUR 317
Description: Fibroblast Growth Factor-2 Human Recombinant (FGF-2) produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 154 amino acids and having a molecular mass of 17.2kDa.;The FGF-b is purified by proprietary chromatographic techniques.

TIMP2 Tissue Inhibitor of Metalloprotease 2 Human Recombinant Protein

PROTP16035-2 Regular: 20ug
EUR 317
Description: TIMP2 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 194 amino acids and having a molecular mass of 21.8kDa. 

IL36G Interleukin-36 Gamma Human Recombinant Protein, His Tag

PROTQ9NZH8-2 Regular: 20ug
EUR 317
Description: IL36G Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 192 amino acids (1-169) and having a molecular mass of 21.1kDa.

IL-12-p40 Interleukin-12 p40 Human Recombinant Protein

PROTP29460-2 Regular: 10ug
EUR 317
Description: Interleukin-12 p40 His Human Recombinant produced in E.Coli is single, a non-glycosylated, polypeptide chain containing 306 amino acids fragment (23-328) with an amino-terminal hexahistidine tag. ;The IL-12 p40 His is purified by proprietary chromatographic techniques.

IL-13-Variant Interleukin-13 Variant Human Recombinant Protein

PROTP35225-2 Regular: 10ug
EUR 317
Description: Interleukin-13 Variant Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 114 amino acids, with a substitution of Q for R at position 112 compared with the wild type IL-13, having a molecular mass of 12.5 kDa. ;The IL-13 Variant is purified by proprietary chromatographic techniques.

IL-16 Interleukin-16 Human Recombinant Protein, His Tag

PROTQ14005-2 Regular: 25ug
EUR 317
Description: Interleukin-16 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain (502-631 a.a) containing 150 amino acids and having a molecular mass of 15.5kDa. The IL-16 is fused to a 20 a.a His-Tag at N-Terminus.;The IL-16 is purified by proprietary chromatographic techniques.

IL-17 Interleukin-17 Human Recombinant Protein, His Tag

PROTQ16552-2 Regular: 10ug
EUR 317
Description: Interleukin-17A Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain containing 132 amino acids fragment (24-155) having a molecular weight of 19.62kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. ;The IL-17A His is purified by proprietary chromatographic techniques.

IL-29 Interleukin-29 Human Recombinant Protein, His Tag

PROTQ8IU54-2 Regular: 20ug
EUR 317
Description: IL 29 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 206 amino acids (20-200 a.a) and having a molecular mass of 22.7kDa.IL 29 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

IL-28A Interleukin-28A Human Recombinant Protein, His Tag

PROTQ8IZJ0-2 Regular: 10ug
EUR 317
Description: IL 28A Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 198 amino acids (26-200 a.a.) and having a molecular mass of 22.1kDa. IL 28A is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

RARRES2 Human, Retinoic Acid Receptor Responder 2 Human Recombinant Protein,Sf9

PROTQ99969-2 Regular: 5ug
EUR 317
Description: RARRES2 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 146 amino acids (21-157a.a.) and having a molecular mass of 16.9kDa. (Molecular size on SDS-PAGE will appear at approximately 18-28kDa). RARRES2 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

TNFR2 Tumor Necrosis Factor Receptor Type 2 Human Recombinant Protein

PROTP20333-2 Regular: 20ug
EUR 317
Description: TNFR2 Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 184 amino acids and having a molecular mass of 20kDa. The TNFR2 is purified by proprietary chromatographic techniques.

LCN2 Neutrophil Gelatinase Associated Lipocalin/Lipocalin-2 Human Recombinant Protein

PROTP80188-2 Regular: 10ug
EUR 317
Description: LCN2 Human Recombinant produced in E.Coli is a homodimeric non-glycosylated polypeptide chains consisting of two 178 amino acids and having a molecular mass of 41.0kDa. 

IL-17F-His Interleukin-17F Human Recombinant Protein,His Tag

PROTQ96PD4-2 Regular: 25ug
EUR 317
Description: IL 17F His Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 158 amino acids (31-163) and having a molecular mass of 17.6kDa.;IL 17F His is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

DCTN2 (1-403) Dynactin 2 (1-403 a.a.) Human Recombinant Protein

PROTQ13561-2 Regular: 20ug
EUR 317
Description: Dynactin 2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 426 amino acids (1-403 a.a) and having a molecular mass of 46.9kDa.;DCTN2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

2-Propyl-β-D-glucuronide, 2 mg

0904-2 2 mg
EUR 162

IL-1-beta Interleukin-1 beta Human Recombinant Protein, His Tag

PROTP01584-2 Regular: 20ug
EUR 317
Description: Interleukin-1 beta His-Tag Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain containing 153 amino acids fragment (117-269) and having a total molecular mass of 21.88 kDa fused with an amino-terminal hexahistidine tag. ;The IL-1b His is purified by proprietary chromatographic techniques.

IL-6 Interleukin-6 Mouse Recombinant Protein, Sf9

PROTP08505-2 Regular: 10ug
EUR 317
Description: Interleukin-6 Mouse Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 193 amino acids (25-211a.a.) and having a molecular mass of 22.5kDa (Molecular size on SDS-PAGE will appear at approximately 18-28kDa). IL6 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

IL-22 Interleukin-22 Mouse Recombinant Protein, Pegylated

PROTQ9JJY9-2 Regular: 10ug
EUR 317
Description: Pegylated Interleukin-22 Mouse Recombinant produced in E.Coli is a single, non-glycosylated homodimeric polypeptide chain containing 147 amino acids and an aditional Ala amino acid at N-terminus having a molecular mass of 36 kDa as determioned by mass spectometry. However due to enlarged hydrodymanic volume it runs on the SDS-PAGE as a 50 kDa protein and in gel-filtration on Superdex 200 as over 200 kDa protein._x000D_ The Murine IL-22 is Mono-pegylated (with 20 kDa PEG) purified by proprietary chromatographic techniques. _x000D_

SOX2 Human, SRY (sex determining region Y)-box 2 Human Recombinant Protein, TAT

PROTP48431-2 Regular: 25ug
EUR 317
Description: Sox2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 330 amino acids (317 aa residues of the full length Sox2) and having a molecular mass of 36kDa.;Sox2 is fused to a 13 amino acid TAT peptide at C-terminus (GGYGRKKRRQRRR) & purified by proprietary chromatographic techniques.

a.a.), TRAIL/APO 2 Ligand (114-281 a.a.) Human Recombinant Protein, Active

PROTP50591-2 Regular: 10ug
EUR 317
Description: Soluble TNF-related apoptosis-inducing ligand Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 169 amino acids _x000D_ (114-281) and having a molecular mass of 19.6 kDa._x000D_ The sTRAIL is purified by proprietary chromatographic techniques.

VEGFR2-Fc Vascular Endothelial Growth Factor Receptor-2 Fc Chimera Human Recombinant Protein

PROTP35968-2 Regular: 10ug
EUR 317
Description: Soluble VEGFR2 Fc Human Recombinant fused with the Fc part of human IgG1 produced in baculovirus is a disulfide-linked homodimeric, glycosylated, polypeptide containing 968 amino acids and having a molecular mass of 145 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding.

IL-8 Interleukin-8 (1-77 a.a) Human Recombinant Protein (CXCL8), His Tag

PROTP10145-2 Regular: 50ug
EUR 317
Description: Interleukin-8 Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 77 amino acids fragment (23-99) and having a total molecular mass of 13.7kDa with an amino-terminal hexahistidine tag. ;The IL-8 His is purified by proprietary chromatographic techniques.

ENO2 Neurone Specific Enolase 2 Human protein

PROTP09104-2 Regular: 20ug
EUR 317
Description: Human Neurone Specific Enolase produced in Human CNS having a molecular mass of 45kDa.

Human Pancreas PrimaCell 2: Pancreatic Epithelial Cells

2-96123 1 Kit Ask for price

IL36A Mouse, Interleukin-36 Alpha Mouse Recombinant Protein, His Tag

PROTQ9JLA2-2 Regular: 20ug
EUR 317
Description: IL36A Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 183 amino acids (1-160 a.a) and having a molecular mass of 20.4kDa. IL36A is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

PG LIVER 2 EA*

59423-2 2 EA
EUR 192.24

Individual Reaction Mix 2

G065-2 200 reactions
EUR 167

Anti-ErbB 2/ERBB2 Antibody

A00010-2 100ug/vial
EUR 334

Anti-Bcl-2/BCL2 Antibody

A00040-2 100ug/vial
EUR 334

Anti-Angiopoietin-2/ANGPT2 Antibody

A00370-2 100ug/vial
EUR 334

Anti-Fascin 2/FSCN2 Antibody

A07840-2 100ug/vial
EUR 294

Bovine KIDNEY WHOLE 2 EA*

57120-2 2 EA
EUR 174.84

Anti-EIF4A1/2/3 Antibody

A03922-2 100ug/vial
EUR 334

pLenti-CARM1 shRNA-2 Plasmid

PVTBAV03691-2 2 ug
EUR 356

pLenti-CTLA4 shRNA-2 Plasmid

PVTBAV05689-2 2 ug
EUR 356

pLenti-FOXM1 shRNA-2 Plasmid

PVTBAV08732-2 2 ug
EUR 356

pLenti-JUN shRNA-2 Plasmid

PVTBAV11741-2 2 ug
EUR 356

pLenti-LHX6 shRNA-2 Plasmid

PVTBAV12881-2 2 ug
EUR 356

pLenti-MAGEA3 shRNA-2 Plasmid

PVTBAV13661-2 2 ug
EUR 356

pLenti-RUNX3 shRNA-2 Plasmid

PVTBAV20583-2 2 ug
EUR 356

pLenti-Slc7a11 shRNA-2 Plasmid

PVTBAV21973-2 2 ug
EUR 356

pLenti-STAT3 shRNA-2 Plasmid

PVTBAV22921-2 2 ug
EUR 356

pLenti-XRCC5 shRNA-2 Plasmid

PVTBAV26238-2 2 ug
EUR 356

Dr. P Kit-Solution 2

K2021010-2 6 ml
EUR 120
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Anti-Interleukin 34/IL34 Antibody

A06903-2 100ug/vial
EUR 334

Anti-Bcl-2 Rabbit Monoclonal Antibody

M00040-2 100ug/vial
EUR 397
Description: Rabbit Monoclonal Bcl-2 Antibody. Validated in IF, WB and tested in Human, Mouse.

Anti-HIF-2-alpha/EPAS1 Antibody

PA1129-2 100ug/vial
EUR 294

Anti-COX2/Cyclooxygenase 2/PTGS2 Antibody

A00084-2 100ug/vial
EUR 294

Anti-p56Dok-2 (Ab-299) Antibody

A07956-2 100ul
EUR 397
Description: Rabbit Polyclonal p56Dok-2 (Ab-299) Antibody. Validated in IF, IHC, WB and tested in Human.

Anti-beta 2 Microglobulin/B2m Antibody

A00456-2 100ug/vial
EUR 294

Anti-VEGF Receptor 2/KDR Antibody

A00901-2 100ug/vial
EUR 334

Anti-Adiponectin Receptor 2 (mouse) Antibody

A02218-2 200ug
EUR 498
Description: Goat Polyclonal Adiponectin Receptor 2 (mouse) Antibody. Validated in IF, IHC and tested in Mouse.

Anti-Anterior Gradient 2/AGR2 Antibody

A02922-2 100ug/vial
EUR 334

Ethyl-β-D-glucuronide, 2 mg

0901-2 2 mg
EUR 162

Ethyl sulfate, sodium salt, 2 mg

0902-2 2 mg
EUR 69

Propyl-β-D-glucuronide, 2 mg

0903-2 2 mg
EUR 162

ExoStd? Lyophilized Exosome Standard (30 µg, Human Plasma, 2 vials)

M1040-2
EUR 593

ExoStd? Lyophilized Exosome Standard (100 µg, Human Plasma, 2 vials)

M1041-2
EUR 711

ExoStd? Lyophilized Exosome Standard (30 µg, Human Serum, 2 vials)

M1042-2
EUR 599

ExoStd? Lyophilized Exosome Standard (100 µg, Human Serum, 2 vials)

M1043-2
EUR 713

ExoStd? Lyophilized Exosome Standard (30 µg, Human Urine, 2 vials)

M1044-2
EUR 599

ExoStd? Lyophilized Exosome Standard (100 µg, Human Urine, 2 vials)

M1045-2
EUR 707

ExoStd? Lyophilized Exosome Standard (30 µg, Human Saliva, 2 vials)

M1046-2
EUR 604

ExoStd? Lyophilized Exosome Standard (100 µg, Human Saliva, 2 vials)

M1047-2
EUR 729

Anti-Beta 2 Microglobulin Antibody (monoclonal, 2H10)

M00456-2 100ug/vial
EUR 334

Mouse Pancreas PrimaCell 2: Pancreatic Epithelial Cells

2-82102 1 Kit Ask for price

Rat Pancreas PrimaCell 2: Pancreatic Epithelial Cells

2-82597 1 Kit Ask for price

Ethyl-β-D-glucuronide-d5, 2 mg

0901D-2 2 mg
EUR 386

Ethyl sulfate-d5, sodium salt, 2 mg

0902D-2 2 mg
EUR 92

Ethyl-β-D-glucuronide-13C6, 2 mg

0905-2 2 mg
EUR 366

IL-2

E13-013-2 50μg
EUR 505

FGF-2

E13-024-2 50μg
EUR 245

Custom Anti-Peptide antibodies 2 peptides (upto 20-aa, synthesis, 2 conjugation, 2 rabbits, 2 ELISA & 2 Aff. Purif.)

ABPEP-20A-2 1
EUR 3806

Anti-COX-2 Rabbit Monoclonal Antibody, Clone#RM348

M00084-2 100uL
EUR 397
Description: Anti-COX-2 Rabbit Monoclonal Antibody, Clone#RM348 tested in WB, IHC, reactive to Human

The disturbed IL-Four decreases the extent of the ACE-2 with the irritation. This additional results in male infertility in COVID-19 sufferers. So, on this speculation, we targeted on the function of IL-Four in COVID-19 sufferers related to male infertility through Th2 cells and JAK-STAT signaling.

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